The Typhi Dot Combo test is a diagnostic tool used to detect the presence of IgG and IgM antibodies against Salmonella typhi, the bacteria responsible for causing typhoid fever. This test is a simple and rapid immunochromatographic assay that requires a small amount of blood sample. The IgG and IgM antibodies are produced by the body’s immune system in response to an infection with S. typhi. The presence of these antibodies in a patient’s blood indicates that they have been exposed to the bacteria and have developed an immune response. The Typhi Dot Combo test is highly specific and sensitive, making it an effective tool for the diagnosis of typhoid fever, especially in areas where the disease is endemic.