The TSH receptor antibodies (TRAb) test is a blood test used to diagnose and monitor certain autoimmune disorders such as Graves’ disease. This test measures the levels of antibodies in the blood that attach to and stimulate the thyroid-stimulating hormone (TSH) receptor on the thyroid gland. In people with Graves’ disease, these antibodies attach to the TSH receptor and cause the thyroid gland to produce excess thyroid hormones, leading to hyperthyroidism. The TRAb test is also used to monitor the effectiveness of treatment for Graves’ disease, as well as to detect the possibility of Graves’ disease in pregnant women with a history of thyroid problems. High levels of TRAb indicate an increased risk of developing Graves’ disease and may require further evaluation and treatment.
